Motif ID: NFY{A,B,C}.p2

Z-value: 2.849


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFYCchr1_+_409300800.703.8e-03Click!
NFYAchr6_+_411486650.048.8e-01Click!
NFYBchr12_-_1030559240.048.9e-01Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_41978464 1.932 NM_017886
ULK4
unc-51-like kinase 4 (C. elegans)
chr5_+_108112537 1.920 FER
fer (fps/fes related) tyrosine kinase
chr7_+_129497637 1.659 KLHDC10
kelch domain containing 10
chr19_-_14467939 1.650 NM_005716
NM_202467
NM_202468
NM_202469
NM_202470
NM_202494
GIPC1





GIPC PDZ domain containing family, member 1





chr11_+_61473931 1.604 NM_001139443
NM_004183
BEST1

bestrophin 1

chr19_-_14467890 1.597 GIPC1
GIPC PDZ domain containing family, member 1
chr7_+_129497572 1.591 NM_014997
KLHDC10
kelch domain containing 10
chr15_-_73719546 1.571 NM_018285
IMP3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr1_-_46370837 1.559 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr1_-_152394215 1.506 NM_001159484
NM_207308
NUP210L

nucleoporin 210kDa-like

chr6_+_160103500 1.479 ACAT2
acetyl-CoA acetyltransferase 2
chr22_-_21193037 1.366 ZNF280B
zinc finger protein 280B
chrX_+_70438352 1.320 NM_012278
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr2_+_85676347 1.320 NM_016494
RNF181
ring finger protein 181
chr7_+_129497808 1.318 KLHDC10
kelch domain containing 10
chr1_-_159257486 1.317 F11R
F11 receptor
chr2_-_96237665 1.314 STARD7
StAR-related lipid transfer (START) domain containing 7
chr6_-_25834733 1.291 NM_170745
HIST1H2AA
histone cluster 1, H2aa
chr6_+_25834983 1.284 NM_170610
HIST1H2BA
histone cluster 1, H2ba
chr6_+_31903374 1.244 NM_005346
HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr21_+_44761927 1.229 C21orf90
chromosome 21 open reading frame 90
chr20_+_47096189 1.219 NM_001316
CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr20_+_47096280 1.195 CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr13_+_48916420 1.172 NM_031915
SETDB2
SET domain, bifurcated 2
chr19_+_45794895 1.172 NM_001042544
LTBP4
latent transforming growth factor beta binding protein 4
chr4_+_166468266 1.150 NM_001017369
NM_006745
SC4MOL

sterol-C4-methyl oxidase-like

chrX_+_53128207 1.140 NM_022117
TSPYL2
TSPY-like 2
chr1_+_43888415 1.115 KDM4A
lysine (K)-specific demethylase 4A
chr2_+_26862416 1.107 CENPA
centromere protein A
chr16_-_10943656 1.106 DEXI
Dexi homolog (mouse)
chr13_+_48916390 1.095 SETDB2
SET domain, bifurcated 2
chr7_-_100021658 1.093 LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr6_+_31891509 1.090 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr1_-_219982016 1.072 DUSP10
dual specificity phosphatase 10
chr22_-_20419975 1.064 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr8_+_74083615 1.058 NM_003218
NM_017489
TERF1

telomeric repeat binding factor (NIMA-interacting) 1

chr15_+_96304911 1.055 NM_183376
ARRDC4
arrestin domain containing 4
chr1_-_159257595 1.053 NM_016946
F11R
F11 receptor
chr18_-_43711143 1.047 SMAD2
SMAD family member 2
chr1_-_219982049 1.035 DUSP10
dual specificity phosphatase 10
chr1_-_203557379 1.034 NM_030952
NUAK2
NUAK family, SNF1-like kinase, 2
chr17_+_70256518 1.033


chr13_+_48916526 1.032 SETDB2
SET domain, bifurcated 2
chr17_+_54587882 0.988 PRR11
proline rich 11
chr20_-_538909 0.988 NM_004609
TCF15
transcription factor 15 (basic helix-loop-helix)
chr19_+_16083706 0.974 RAB8A
RAB8A, member RAS oncogene family
chr1_-_159257567 0.973 F11R
F11 receptor
chr14_+_23711044 0.967 NM_001048205
NM_005132
REC8

REC8 homolog (yeast)

chr6_+_43005214 0.964 CNPY3
canopy 3 homolog (zebrafish)
chr17_-_17883051 0.944 NM_145691
ATPAF2
ATP synthase mitochondrial F1 complex assembly factor 2
chr7_-_150305933 0.942 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr17_-_8000362 0.942 PER1
period homolog 1 (Drosophila)
chr10_+_4858321 0.940 NM_001040177
AKR1E2
aldo-keto reductase family 1, member E2
chr15_+_96304942 0.937 ARRDC4
arrestin domain containing 4
chr1_-_195382189 0.924 NM_018136
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr2_-_128501206 0.904 SAP130
Sin3A-associated protein, 130kDa
chr12_+_27568311 0.896 NM_001198915
NM_001198916
NM_003622
NM_177444
PPFIBP1



PTPRF interacting protein, binding protein 1 (liprin beta 1)



chr7_+_99974781 0.895 AGFG2
ArfGAP with FG repeats 2
chr8_+_6553543 0.888 AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr1_-_39097904 0.881 NM_022157
RRAGC
Ras-related GTP binding C
chr10_-_101370076 0.880 SLC25A28
solute carrier family 25, member 28
chr1_-_219982081 0.879 NM_007207
NM_144729
DUSP10

dual specificity phosphatase 10

chr3_-_37009571 0.879


chr16_-_10943716 0.862 NM_014015
DEXI
Dexi homolog (mouse)
chr19_-_54350457 0.861 NM_002152
HRC
histidine rich calcium binding protein
chr12_+_122283796 0.859 NM_152269
NM_001194995
C12orf65

chromosome 12 open reading frame 65

chr17_+_44643067 0.857 ABI3
ABI family, member 3
chr6_-_31938530 0.846 NEU1
sialidase 1 (lysosomal sialidase)
chr14_+_28305922 0.846 NM_005249
FOXG1
forkhead box G1
chr1_+_43888391 0.842 KDM4A
lysine (K)-specific demethylase 4A
chr19_+_55398680 0.839 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr3_+_187771192 0.838 DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr19_-_14089362 0.826 NM_002730
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr1_-_35431318 0.826 SFPQ
splicing factor proline/glutamine-rich
chr3_-_37009592 0.822 EPM2AIP1
EPM2A (laforin) interacting protein 1
chr16_-_83209185 0.821 COTL1
coactosin-like 1 (Dictyostelium)
chr4_-_110942783 0.815 NM_000204
CFI
complement factor I
chr14_-_63178287 0.809 NM_080666
WDR89
WD repeat domain 89
chr19_-_38154631 0.807 NM_032816
CCDC123
coiled-coil domain containing 123
chr16_+_1772929 0.801 NM_012225
NUBP2
nucleotide binding protein 2 (MinD homolog, E. coli)
chr1_-_166149867 0.798 NM_001167749
NM_018417
ADCY10

adenylate cyclase 10 (soluble)

chr3_+_37009987 0.793 MLH1
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
chr17_-_44037332 0.793 NM_018952
HOXB6
homeobox B6
chr7_+_149166411 0.793 ZNF862
zinc finger protein 862
chr1_-_35431329 0.792 NM_005066
SFPQ
splicing factor proline/glutamine-rich
chr17_+_43374021 0.790 PNPO
pyridoxamine 5'-phosphate oxidase
chr1_-_149586298 0.787 RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr12_-_55013987 0.783 NM_001166279
NM_014871
PAN2

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

chr6_-_31938572 0.780 NM_000434
NEU1
sialidase 1 (lysosomal sialidase)
chr19_+_50086299 0.778 NM_001128916
NM_001128917
NM_006114
TOMM40


translocase of outer mitochondrial membrane 40 homolog (yeast)


chrX_-_50403412 0.777 SHROOM4
shroom family member 4
chr17_-_71287417 0.767 NM_005324
H3F3B
H3 histone, family 3B (H3.3B)
chr12_+_88627601 0.766 LOC338758
hypothetical LOC338758
chr1_-_28113817 0.763 NM_002946
RPA2
replication protein A2, 32kDa
chr19_-_12858956 0.754 NM_006563
KLF1
Kruppel-like factor 1 (erythroid)
chr1_-_109742020 0.741 NM_002959
SORT1
sortilin 1
chr6_+_15354278 0.740 NM_004973
JARID2
jumonji, AT rich interactive domain 2
chr16_-_83209140 0.737 NM_021149
COTL1
coactosin-like 1 (Dictyostelium)
chr3_+_199171467 0.736 NM_001136049
NM_033029
LMLN

leishmanolysin-like (metallopeptidase M8 family)

chr17_-_77411733 0.735 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr7_+_99974720 0.730 NM_006076
AGFG2
ArfGAP with FG repeats 2
chr2_-_97646758 0.728 ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr8_+_11697929 0.727 FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr16_+_1773004 0.725 NUBP2
nucleotide binding protein 2 (MinD homolog, E. coli)
chrX_+_47999740 0.725 NM_005635
SSX1
synovial sarcoma, X breakpoint 1
chr8_+_6553278 0.724 NM_018361
AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr2_-_61618898 0.724 NM_003400
XPO1
exportin 1 (CRM1 homolog, yeast)
chr2_-_128501334 0.719 NM_001145928
NM_024545
SAP130

Sin3A-associated protein, 130kDa

chr6_+_31891293 0.719 HSPA1A
heat shock 70kDa protein 1A
chr3_-_130385454 0.716 NM_001127192
NM_001127193
NM_001127194
NM_001127195
NM_001127196
NM_003418
CNBP





CCHC-type zinc finger, nucleic acid binding protein





chr19_-_6688270 0.716 NM_020171
GPR108
G protein-coupled receptor 108
chr7_-_135063461 0.711 NM_012450
SLC13A4
solute carrier family 13 (sodium/sulfate symporters), member 4
chr22_+_22737753 0.710 NM_012295
CABIN1
calcineurin binding protein 1
chr4_-_110942576 0.708 CFI
complement factor I
chr17_-_77411695 0.708 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr9_+_132990834 0.705 NUP214
nucleoporin 214kDa
chr9_-_127043169 0.701 HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr16_-_83209020 0.700 COTL1
coactosin-like 1 (Dictyostelium)
chr19_-_14089560 0.698 PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr9_-_35804997 0.697 HINT2
histidine triad nucleotide binding protein 2
chr1_-_35431017 0.697 SFPQ
splicing factor proline/glutamine-rich
chr2_+_96237851 0.696 LOC285033
hypothetical protein LOC285033
chr20_-_31737815 0.696 NM_005225
E2F1
E2F transcription factor 1
chr6_+_24511123 0.695 NM_020662
MRS2
MRS2 magnesium homeostasis factor homolog (S. cerevisiae)
chr1_+_153545162 0.693 NM_001135822
NM_002004
FDPS

farnesyl diphosphate synthase

chr18_-_43710917 0.692 NM_005901
SMAD2
SMAD family member 2
chr16_-_10943778 0.691 DEXI
Dexi homolog (mouse)
chr2_+_223433919 0.689 NM_004457
NM_203372
ACSL3

acyl-CoA synthetase long-chain family member 3

chr19_+_16083549 0.683 RAB8A
RAB8A, member RAS oncogene family
chr1_+_153545301 0.677 NM_001135821
FDPS
farnesyl diphosphate synthase
chr6_-_83014160 0.676 NM_015525
IBTK
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr2_+_27127994 0.676 NM_001035507
NM_021831
AGBL5

ATP/GTP binding protein-like 5

chrX_+_49013243 0.675 NM_001184745
NM_033215
PPP1R3F

protein phosphatase 1, regulatory (inhibitor) subunit 3F

chr17_-_44642934 0.672 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr13_-_48916144 0.671 NM_001079670
CAB39L
calcium binding protein 39-like
chr7_+_133982070 0.671 NM_001724
NM_199186
BPGM

2,3-bisphosphoglycerate mutase

chr2_+_74539039 0.670 NM_012477
WBP1
WW domain binding protein 1
chr6_-_136613097 0.670 NM_001099286
NM_138419
FAM54A

family with sequence similarity 54, member A

chr7_-_137337318 0.669 CREB3L2
cAMP responsive element binding protein 3-like 2
chr1_-_35795592 0.666 NM_024874
KIAA0319L
KIAA0319-like
chr7_+_149166441 0.658 NM_001099220
ZNF862
zinc finger protein 862
chr7_-_72735665 0.656 NM_032317
DNAJC30
DnaJ (Hsp40) homolog, subfamily C, member 30
chr3_-_42820915 0.653 NM_001099668
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chrX_+_151750166 0.652 NM_001129765
NM_015922
NSDHL

NAD(P) dependent steroid dehydrogenase-like

chr16_-_1816529 0.652 HAGH
hydroxyacylglutathione hydrolase
chr9_-_35805040 0.649 NM_032593
HINT2
histidine triad nucleotide binding protein 2
chr2_+_27128024 0.648 AGBL5
ATP/GTP binding protein-like 5
chr11_-_62355128 0.647 STX5
syntaxin 5
chr14_-_22825072 0.647 HOMEZ
homeobox and leucine zipper encoding
chr1_-_115014151 0.647 NM_198459
DENND2C
DENN/MADD domain containing 2C
chr7_-_137337352 0.646 CREB3L2
cAMP responsive element binding protein 3-like 2
chr1_+_12002138 0.643 MIIP
migration and invasion inhibitory protein
chr11_+_57236617 0.643 NM_001144012
NM_015959
TMX2-CTNND1
TMX2

TMX2-CTNND1 read-through transcript
thioredoxin-related transmembrane protein 2

chr17_+_43373887 0.642 NM_018129
PNPO
pyridoxamine 5'-phosphate oxidase
chr1_-_52116598 0.642 NRD1
nardilysin (N-arginine dibasic convertase)
chr12_+_54904371 0.640 NM_024068
OBFC2B
oligonucleotide/oligosaccharide-binding fold containing 2B
chr10_-_69267774 0.640 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr10_-_101370147 0.640 SLC25A28
solute carrier family 25, member 28
chr1_-_226679648 0.638 NM_003493
HIST3H3
histone cluster 3, H3
chr3_+_67131416 0.637 NM_032505
KBTBD8
kelch repeat and BTB (POZ) domain containing 8
chr15_+_39310693 0.637 NM_007236
CHP
calcium binding protein P22
chr12_+_110689094 0.636 ALDH2
aldehyde dehydrogenase 2 family (mitochondrial)
chr1_+_43888382 0.634 NM_014663
KDM4A
lysine (K)-specific demethylase 4A
chr17_+_18700385 0.632 PRPSAP2
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr1_-_23567084 0.627 NM_030634
ZNF436
zinc finger protein 436
chr1_+_165957780 0.626 NM_001146191
NM_003953
NM_024569
MPZL1


myelin protein zero-like 1


chrX_-_46889036 0.626 NM_001135998
NM_019056
NDUFB11

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa

chr16_+_1817209 0.625 NM_001018104
NM_001142398
NM_031208
FAHD1


fumarylacetoacetate hydrolase domain containing 1


chr20_-_48203709 0.622 NM_001162505
NM_199129
NM_199203
TMEM189

TMEM189-UBE2V1
transmembrane protein 189

TMEM189-UBE2V1 readthrough
chr19_+_2928480 0.618 NM_001143986
NM_024760
TLE6

transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)

chr1_-_19101603 0.618 NM_003748
NM_170726
ALDH4A1

aldehyde dehydrogenase 4 family, member A1

chr9_+_132990760 0.617 NM_005085
NUP214
nucleoporin 214kDa
chr1_-_35795589 0.616 KIAA0319L
KIAA0319-like
chr9_-_100057313 0.616 TBC1D2
TBC1 domain family, member 2
chr14_+_23710924 0.615 REC8
REC8 homolog (yeast)
chr19_-_17377383 0.614 NM_004335
BST2
bone marrow stromal cell antigen 2
chr17_+_44325127 0.614 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chrX_-_100549444 0.607 GLA
galactosidase, alpha
chr1_+_201541269 0.606 NM_006763
BTG2
BTG family, member 2
chr19_-_3922032 0.606 DAPK3
death-associated protein kinase 3
chr11_-_46824364 0.605 CKAP5
cytoskeleton associated protein 5
chr22_-_21193504 0.600 NM_080764
ZNF280B
zinc finger protein 280B
chrX_+_151750221 0.599 NSDHL
NAD(P) dependent steroid dehydrogenase-like
chr2_-_3360467 0.598 NM_003310
TSSC1
tumor suppressing subtransferable candidate 1
chrX_+_38545597 0.598 NM_001098790
NM_001098791
MID1IP1

MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))

chr17_-_35827568 0.598 NM_001067
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr1_-_149586341 0.594 NM_000449
NM_001025603
RFX5

regulatory factor X, 5 (influences HLA class II expression)

chr12_-_118799457 0.592 NM_007174
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr22_-_17815211 0.588 C22orf39
HIRA
chromosome 22 open reading frame 39
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr14_-_34001164 0.588 NM_138288
C14orf147
chromosome 14 open reading frame 147
chr2_-_157890400 0.587 NM_020711
ERMN
ermin, ERM-like protein
chr1_+_166516901 0.586 NM_005149
TBX19
T-box 19
chr22_+_20326572 0.585 SDF2L1
stromal cell-derived factor 2-like 1
chr20_-_5048443 0.582 NM_182649
PCNA
proliferating cell nuclear antigen
chr11_-_46824416 0.579 NM_001008938
NM_014756
CKAP5

cytoskeleton associated protein 5

chr6_-_83014106 0.579 IBTK
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr14_+_73621408 0.578 NM_001024674
LIN52
lin-52 homolog (C. elegans)
chr19_-_19110268 0.576 TMEM161A
transmembrane protein 161A
chr9_-_35804982 0.576


chr19_+_47416338 0.576 ZNF526
zinc finger protein 526

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.94 3.51e-17 GO:0007049 cell cycle
2.18 4.46e-17 GO:0022403 cell cycle phase
2.04 3.95e-16 GO:0022402 cell cycle process
2.44 2.60e-15 GO:0000279 M phase
2.20 1.30e-14 GO:0000278 mitotic cell cycle
1.64 1.02e-13 GO:0006996 organelle organization
1.26 2.12e-13 GO:0044237 cellular metabolic process
1.33 5.49e-13 GO:0044260 cellular macromolecule metabolic process
2.07 1.99e-12 GO:0051276 chromosome organization
2.57 3.97e-12 GO:0000087 M phase of mitotic cell cycle
1.49 3.43e-11 GO:0090304 nucleic acid metabolic process
1.42 9.24e-11 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.01 1.75e-10 GO:0006259 DNA metabolic process
1.23 3.56e-10 GO:0044238 primary metabolic process
1.37 5.85e-10 GO:0034641 cellular nitrogen compound metabolic process
2.44 8.25e-10 GO:0000280 nuclear division
2.44 8.25e-10 GO:0007067 mitosis
3.50 1.49e-09 GO:0007059 chromosome segregation
1.20 1.61e-09 GO:0008152 metabolic process
2.28 2.81e-09 GO:0010564 regulation of cell cycle process
2.29 2.82e-09 GO:0006281 DNA repair
3.11 3.28e-09 GO:0006310 DNA recombination
1.35 3.47e-09 GO:0006807 nitrogen compound metabolic process
2.65 4.27e-09 GO:0000075 cell cycle checkpoint
3.40 4.29e-09 GO:0065004 protein-DNA complex assembly
2.36 4.53e-09 GO:0048285 organelle fission
3.30 6.61e-09 GO:0071824 protein-DNA complex subunit organization
2.59 7.40e-09 GO:0071156 regulation of cell cycle arrest
3.13 7.69e-09 GO:0006323 DNA packaging
1.90 9.26e-09 GO:0051726 regulation of cell cycle
2.22 1.80e-08 GO:0051301 cell division
1.75 3.02e-08 GO:0033554 cellular response to stress
2.88 3.89e-08 GO:0071103 DNA conformation change
1.25 4.02e-08 GO:0043170 macromolecule metabolic process
2.00 8.06e-08 GO:0006325 chromatin organization
3.41 1.04e-07 GO:0006334 nucleosome assembly
1.38 1.25e-07 GO:0009058 biosynthetic process
3.26 1.25e-07 GO:0034728 nucleosome organization
1.38 4.89e-07 GO:0044249 cellular biosynthetic process
3.23 5.42e-07 GO:0031497 chromatin assembly
4.78 9.03e-07 GO:0016126 sterol biosynthetic process
2.79 1.43e-06 GO:0006333 chromatin assembly or disassembly
1.88 1.59e-06 GO:0006974 response to DNA damage stimulus
5.08 1.86e-06 GO:0006695 cholesterol biosynthetic process
3.37 2.01e-06 GO:0000236 mitotic prometaphase
1.33 5.44e-06 GO:0071841 cellular component organization or biogenesis at cellular level
1.33 6.63e-06 GO:0071842 cellular component organization at cellular level
2.07 2.51e-05 GO:0051325 interphase
2.04 7.51e-05 GO:0051329 interphase of mitotic cell cycle
2.32 1.79e-04 GO:0006260 DNA replication
1.09 2.08e-04 GO:0009987 cellular process
1.89 3.49e-04 GO:0034622 cellular macromolecular complex assembly
8.28 3.86e-04 GO:0002566 somatic diversification of immune receptors via somatic mutation
8.28 3.86e-04 GO:0016446 somatic hypermutation of immunoglobulin genes
1.38 5.70e-04 GO:0034645 cellular macromolecule biosynthetic process
1.37 6.29e-04 GO:0009059 macromolecule biosynthetic process
3.73 8.72e-04 GO:0000819 sister chromatid segregation
1.45 1.39e-03 GO:0044248 cellular catabolic process
1.84 1.46e-03 GO:0016568 chromatin modification
2.57 2.19e-03 GO:0007126 meiosis
2.57 2.19e-03 GO:0051327 M phase of meiotic cell cycle
1.28 2.23e-03 GO:0044267 cellular protein metabolic process
2.54 2.70e-03 GO:0051321 meiotic cell cycle
5.13 3.83e-03 GO:0006298 mismatch repair
2.07 7.13e-03 GO:0006457 protein folding
1.39 8.10e-03 GO:0051641 cellular localization
3.55 8.50e-03 GO:0000070 mitotic sister chromatid segregation
2.54 9.29e-03 GO:0006694 steroid biosynthetic process
1.65 1.19e-02 GO:0034621 cellular macromolecular complex subunit organization
1.32 1.19e-02 GO:0016070 RNA metabolic process
4.04 1.34e-02 GO:0007131 reciprocal meiotic recombination
1.21 2.44e-02 GO:0016043 cellular component organization
1.20 2.81e-02 GO:0071840 cellular component organization or biogenesis
1.30 3.03e-02 GO:0010467 gene expression
3.79 3.16e-02 GO:0000724 double-strand break repair via homologous recombination
3.79 3.16e-02 GO:0000725 recombinational repair
1.59 3.56e-02 GO:0044265 cellular macromolecule catabolic process
2.58 3.64e-02 GO:0051656 establishment of organelle localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.34 3.04e-50 GO:0043231 intracellular membrane-bounded organelle
1.34 6.29e-50 GO:0043227 membrane-bounded organelle
1.30 2.61e-49 GO:0043229 intracellular organelle
1.29 9.28e-49 GO:0043226 organelle
1.23 1.42e-48 GO:0044424 intracellular part
1.22 6.23e-48 GO:0005622 intracellular
1.46 2.52e-38 GO:0005634 nucleus
1.40 1.28e-29 GO:0044446 intracellular organelle part
1.40 2.00e-29 GO:0044422 organelle part
1.63 3.06e-21 GO:0070013 intracellular organelle lumen
2.42 4.41e-21 GO:0005694 chromosome
1.63 4.25e-20 GO:0044428 nuclear part
1.60 4.97e-20 GO:0031974 membrane-enclosed lumen
1.60 6.43e-20 GO:0043233 organelle lumen
2.46 2.03e-18 GO:0044427 chromosomal part
1.20 1.54e-15 GO:0005737 cytoplasm
1.59 1.76e-14 GO:0031981 nuclear lumen
1.44 1.33e-13 GO:0043228 non-membrane-bounded organelle
1.44 1.33e-13 GO:0043232 intracellular non-membrane-bounded organelle
1.26 1.39e-13 GO:0044444 cytoplasmic part
1.64 1.07e-11 GO:0005654 nucleoplasm
1.34 4.04e-11 GO:0032991 macromolecular complex
1.86 5.05e-10 GO:0015630 microtubule cytoskeleton
2.93 9.66e-09 GO:0000793 condensed chromosome
2.40 2.87e-08 GO:0000785 chromatin
2.52 8.84e-07 GO:0044454 nuclear chromosome part
3.07 1.36e-06 GO:0032993 protein-DNA complex
2.31 2.35e-06 GO:0000228 nuclear chromosome
2.61 3.56e-06 GO:0000775 chromosome, centromeric region
3.61 3.62e-06 GO:0000786 nucleosome
1.29 5.29e-06 GO:0043234 protein complex
1.44 1.93e-05 GO:0005739 mitochondrion
1.64 2.01e-05 GO:0044429 mitochondrial part
2.32 2.21e-05 GO:0005819 spindle
3.19 3.14e-05 GO:0000777 condensed chromosome kinetochore
3.11 3.23e-05 GO:0000779 condensed chromosome, centromeric region
1.04 6.41e-05 GO:0044464 cell part
1.04 6.67e-05 GO:0005623 cell
1.32 1.44e-04 GO:0005829 cytosol
2.83 1.62e-04 GO:0000776 kinetochore
3.39 2.13e-04 GO:0000794 condensed nuclear chromosome
1.55 4.19e-04 GO:0031967 organelle envelope
1.53 1.00e-03 GO:0031975 envelope
1.93 1.02e-03 GO:0005759 mitochondrial matrix
6.21 2.75e-03 GO:0032300 mismatch repair complex
1.50 3.33e-03 GO:0044451 nucleoplasm part
5.93 1.73e-02 GO:0032391 photoreceptor connecting cilium
1.74 1.86e-02 GO:0005874 microtubule
1.54 2.16e-02 GO:0030529 ribonucleoprotein complex
1.29 2.35e-02 GO:0005856 cytoskeleton
2.60 3.11e-02 GO:0034399 nuclear periphery
1.81 3.61e-02 GO:0005813 centrosome
7.77 3.72e-02 GO:0032389 MutLalpha complex
1.42 3.76e-02 GO:0044432 endoplasmic reticulum part
1.65 4.02e-02 GO:0005815 microtubule organizing center
2.69 4.90e-02 GO:0030496 midbody

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.22 5.26e-14 GO:0005515 protein binding
1.11 5.12e-12 GO:0005488 binding
1.32 1.59e-08 GO:0003676 nucleic acid binding
1.33 1.01e-05 GO:0003677 DNA binding
1.18 5.95e-05 GO:0003824 catalytic activity
9.32 1.20e-04 GO:0032404 mismatch repair complex binding
3.86 2.71e-04 GO:0003678 DNA helicase activity
5.99 1.65e-03 GO:0030983 mismatched DNA binding
2.91 4.97e-03 GO:0008094 DNA-dependent ATPase activity
3.91 5.62e-03 GO:0004003 ATP-dependent DNA helicase activity
1.26 6.54e-03 GO:0000166 nucleotide binding
1.31 1.10e-02 GO:0030554 adenyl nucleotide binding
1.31 1.79e-02 GO:0005524 ATP binding
1.30 2.27e-02 GO:0032559 adenyl ribonucleotide binding
1.45 2.71e-02 GO:0019899 enzyme binding
1.43 3.23e-02 GO:0016817 hydrolase activity, acting on acid anhydrides
1.66 3.54e-02 GO:0016887 ATPase activity
1.42 4.27e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides